منابع مشابه
Pharmacogenetics of analgesic drugs
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. • Analgesics act in various ways on the peripheral and central pain pathways and are regarded as one of the most valuable but equally dangerous groups of medications. • While pharmacokinetic properties of drugs, metabolism in particular, ...
متن کاملAdverse effects of opioid analgesic drugs.
Opioids were available in clinical practice since before the birth of modern anaesthesia--Setürner isolated morphine in 1806. They have a record of safety which is reflected in their high therapeutic ratios, especially the synthetic opioids introduced recently (table III). The most serious immediate adverse effect, respiratory depression, is a predictable effect related closely to analgesia. It...
متن کاملBotanical Analgesic and Anti-inflammatory Drugs
Contents 1. Introduction 2. Principal plants that have contributed to the development of modern analgesic and anti-inflammatory drugs 2.1. Papaver somniferum 2.2. Salix species 2.3. Cannabis sativa 2.4. Capsicum sp. 2.5. Panax ginseng 2.6. Tanacetum parthenium 2.7. Aconitum sp. 3. New plant-derived substances with potential antinociceptive or anti-inflammatory properties 3.1 Siphocampylus verti...
متن کاملRegular use of analgesic drugs and ovarian cancer risk.
Analgesics have been shown to reduce risk for colorectal cancer. Results from three recent reports (D. W. Cramer et al., Lancet, 351: 104-107, 1998; C. Rodriguez et. al., Lancet, 352: 1354-1355, 1998; L. Rosenberg et al., Cancer Epidemiol. Biomark. Prev., 9: 933-937, 2000) suggest that these drugs might be associated with decreased risk for ovarian cancer. In this hospital-based case-control st...
متن کاملAnalgesic and Antineuropathic Drugs Acting Through Central Cholinergic Mechanisms
The role of muscarinic and nicotinic cholinergic receptors in analgesia and neuropathic pain relief is relatively unknown. This review describes how such drugs induce analgesia or alleviate neuropathic pain by acting on the central cholinergic system. Several pharmacological strategies are discussed which increase synthesis and release of acetylcholine (ACh) from cholinergic neurons. The effect...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 1960
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5178.1039